Single Cell and Spatial Omics
Single cell omics analysis is an emerging discipline that stems from various “omics” technologies, particularly genomics, transcriptomics, and epigenomics, where the sensitivity is improved to a single cell level. Applying these technologies at the single cell level is crucial since every cell is specific and unique; nearly every cell population, derived in vivo or in vitro, is heterogeneous. Single cell omics analysis is providing unprecedented resolution for the understanding of tissues and systems, and the interaction of single cells on a global scale.
Spatial omics is where the quantification of expression of large numbers of gene or proteins within the spatial context of tissues and cells is undertaken.
Services and resources
Access bioinformatics and data analysis tools without the need to code.
A set of pipelines to process 10X Chromium single cell data to align reads, generate feature-barcode matrices, perform clustering and other analyses.
For researchers wanting to use Nextflow bioinformatics pipelines across a myriad of compute platforms.
Access computational resources to generate genomic data assets.
Find scientific computational workflows for your genomics analyses or share your own in a range of workflow types.
Find where genomics tools are installed and optimised across our national computational partner network.
A central collection of how-to guides prepared by BioCommons community members
BioCommons training including genomics themed webinars, discussions and workshops.
Freely available via the Galaxy Training Network.
Join the conversation - all welcome!
We help coordinate a community for single cell and spatial omics, which aims to:
Provide a forum to:
Connect with colleagues, share knowledge and collaborate
Learn about how to leverage relevant tools and services
Identify gaps in current community scale digital infrastructure.
This approach helps us identify and deploy relevant national scale services and resources that help address these gaps.
Infrastructure roadmap
We have been engaging with a broad group of Australian researchers since 2022 to develop a Single Cell and Spatial Omics Infrastructure Roadmaps for Australia, which present a community vision for shared national infrastructure that will help researchers undertake genomics analyses.
The Roadmap acts as a blueprint to inform the work we do with various partners to deploy the services and resources listed above that help address the challenges.
The roadmaps are updated regularly to denote progress with the services that have been deployed by the Australian BioCommons and partners to support Single Cell and Spatial Omics analysis in Australia.